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Revista médica del Hospital General de México

versão On-line ISSN 2524-177Xversão impressa ISSN 0185-1063

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VILLACIS-VASQUEZ, María R.  e  BARAHONA-ULLOA, Wilson F.. Miller Fisher variant Guillain-Barre syndrome: A case review. Rev. med. Hosp. Gen. Méx. [online]. 2021, vol.84, n.3, pp.129-135.  Epub 06-Set-2021. ISSN 2524-177X.  https://doi.org/10.24875/hgmx.20000063.

Female patient presents respiratory infection 1 month before the appearance of following triad: ophthalmoplegia, ataxia, and hyporeflexia. Diagnosed as Miller Fisher syndrome, associated with cytomegalovirus infection, that showed an aggressive pattern in anti-GQ1b antibodies as well as albuminocytological dissociation in cerebrospinal fluid and demyelination in electromyography, without therapeutic response to intravenous immunoglobulin and plasmapheresis. The progression of the disorder leads to overlap with a classic Guillain-Barré syndrome, presented by the persistence of quadriparesis and dysphagia for solids/liquids, reflecting a poor prognosis, confirming that the etiologic agent has impact on the aggressiveness. This is also indicated in up-to-date literature, which justifies the importance of report.

Palavras-chave : Autoimmune diseases of the nervous system; Polyradiculoneuropathy; Guillain-Barré; syndrome; Miller Fisher syndrome; Cytomegalovirus.

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