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Revista alergia México
On-line version ISSN 2448-9190
Abstract
CARDONA, Ricardo et al. Mast cell activation syndrome. About a clinical case. Rev. alerg. Méx. [online]. 2019, vol.66, n.4, pp.504-509. Epub Sep 25, 2020. ISSN 2448-9190. https://doi.org/10.29262/ram.v66i4.587.
Background:
Monoclonal mast cell activation syndrome is included in mast cell activation disorders in which, after a diagnostic process, it is not possible to meet the required criteria for a diagnosis of systemic mastocytosis.
Clinical case:
A 73-year-old woman who presented two events of anaphylaxis 15 minutes after the intake of yucca; with a positive skin test, elevated tryptase, and mast cells with abnormal phenotype in the bone marrow biopsy, and without criteria for systemic mastocytosis.
Conclusions:
The diagnosis of monoclonal mast cell activation syndrome requires high clinical suspicion for patients with recurrent anaphylaxis and elevated tryptase, for whom joint management with hematology is essential.
Keywords : Mastocytosis; Anaphylaxis; Tryptase.
