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Revista alergia México

On-line version ISSN 2448-9190


GELARDI, Matteo et al. The role of the fern test in the treatment of rhinitis. Rev. alerg. Méx. [online]. 2019, vol.66, n.2, pp.184-191. ISSN 2448-9190.


The fern test is a method for assessing the characteristics of the nasal section in the treatment of patients with mucous dysfunction of the airway.

Objective: The aim of this study was to investigate the role of the fern test in patients with rhinitis and to assess the classification of each type of rhinitis (types I-IV) in clinical practice.


A cross-sectional study, which included consecutive patients from a third level Rhinology Unit, worked with 182 patients with rhinitis and 30 healthy subjects as control. The patients were subdivided according to their type of rhinitis: allergic rhinitis (59), infectious rhinitis (32), polyps (31), NARES (Non-allergic rhinitis with eosinophilia syndrome) (30) and NARNE (non-allergic rhinitis with neutrophils) (30).


The control subjects had only type I or II rhinitis, whereas patients with rhinitis usually showed type III or IV. Allergic rhinitis and nasal polyps had the most serious deterioration according to the fern test (type IV).


The fern test is effective for assessing mucus alterations in patients with rhinitis and it could be included as a new parameter in the study of rhinitis as a potential biomarker of the function of damaged epithelial cells.

Keywords : Rhinitis; Fern test; Inflammation of the mucosa.

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