SciELO - Scientific Electronic Library Online

vol.65 issue2Common variable immunodeficiency and its association with memory B-cell defectsAdverse reaction to food additives in a pediatric patient author indexsubject indexsearch form
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • Have no similar articlesSimilars in SciELO


Revista alergia México

On-line version ISSN 2448-9190


ZURITA-CRUZ, Jessie Nallely; MARQUEZ-GONZALEZ, Horacio; MIRANDA-NOVALES, Guadalupe  and  VILLASIS-KEEVER, Miguel Ángel. Experimental studies: research designs for the evaluation of interventions in clinical settings. Rev. alerg. Méx. [online]. 2018, vol.65, n.2, pp.178-186. ISSN 2448-9190.

Experimental studies are used to assess the efficacy and effectiveness of therapeutic (pharmacological or surgical), preventive (such as vaccination or lifestyle changes) or educational interventions (e.g., workshops to improve quality and healthcare). There are different experimental studies but, currently, randomized controlled trial (RCT) is recognized as the type of study that provides the highest level of evidence. When this type of research cannot be carried out, there are quasi-experimental studies, where there may be no randomization or a control group; however, this type of studies has a lower degree of validity. This article describes the way different types of RCT and quasi-experimental studies are performed; their advantages and disadvantages are also explained.

Keywords : Experimental study; Randomized controlled trial; Quasi-experimental study.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )