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Medicina crítica (Colegio Mexicano de Medicina Crítica)

versión impresa ISSN 2448-8909

Resumen

RODRIGUEZ DE MOLINA SERRANO, José Iván; CASTRO MARTINEZ, Hugo Humberto; OYARVIDE ZAPUCHE, Ana Karen  y  FLORES ORTA, Gustavo Adolfo. Lung protective ventilation, mechanical power, driving pressure and its relation to mortality and SOFA in patients with invasive mechanical ventilation. Med. crít. (Col. Mex. Med. Crít.) [online]. 2021, vol.35, n.4, pp.186-193.  Epub 16-Feb-2022. ISSN 2448-8909.

Introduction:

Mechanical ventilation is the cornerstone of the treatment of patients with acute respiratory failure, however, it is not free of complications and eventual adverse events.

Objective:

To describe the relationship between EVPP, PM and PDP with mortality and SOFA in adult patients with IMV attended at HGZ No. 11, IMSS, Piedras Negras, Coahuila.

Material and methods:

Prospective, observational study, September 2019 to March 2020 of adult patients with invasive mechanical ventilation. The independent variable was LPV, MP and DP. The dependent variables were mortality and SOFA.

Results:

63 patients were enrolled. Main characteristics: age 55 years female 44.4%, location: ward 50.8%, ER 17.5% and ICU 31.8%. Diagnoses: sepsis 20.6%, severe TBI 7.8%, stroke 7.8%, CAP 6.4% and others 57.4%. Hospital mortality 77.8%. Factors associated with mortality: age OR 1.09 (p = 0.01) and plateau pressure OR 1.3 (p = 0.03); DP OR 1.4 (p = 0.12), MP OR 0.79 (p = 0.07) and LPV OR 1.5 (p = 0.7). Factors associated with SOFA: SAPS 3 (r) = 0.53 p < 0.0001. SMR 1.06 95% CI 0.80-1.4 p = 0.63.

Conclusions:

LPV, DP and MP were not related to mortality or SOFA in this cohort of patients.

Palabras llave : Lung protective ventilation; mechanical power; pulmonary distention pressure; mortality; SOFA.

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