Objective:

To compare the prognosis of women admitted to the intensive care unit of the National Institute of Perinatology for severe preeclampsia and SARS-CoV-2 infection, measuring the correlation between viral load and maternal complications.

Material and methods:

Study of a cohort of women with pre-eclampsia admitted to an Intensive Care Unit, by non-probabilistic sampling per consecutive case of 105 women in the period from March 1, 2020 to October 15, 2020, for whom a count of platelets, aminotransferases, protein/creatinine ratio in casual urine (mg/dL), urea and creatinine, and demographic data in the first hours of admission.

Results:

There were no differences in the number of maternal complications between COVID-19-positive women with severe preeclampsia (27.5%) versus COVID-19-negative women (23.6%), p = 0.58. A positive COVID-19 test did not increase the risk of maternal complications OR 1.31 (95% CI, 0.495-3.47). The degree of proteinuria was higher in women with a positive test. Pneumonia associated with COVID-19 was considered in 27.5% of positive women. There was a better correlation between the variables of blood pressure and the AST/ALT ratio in women with pneumonia and viral load.

Conclusions:

The present study shows that in women with severe preeclampsia treated in the intensive care unit, maternal complications do not increase when there is SARS-CoV-2 infection.

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