Abstract

ESPINOZA VILLAFUERTE, Missael V; MARTINEZ ZUBIETA, Ricardo  and  ZARAGOZA GALVAN, José J. Relationship between chronic beta-blockers usage and mortality in sepsis and septic shock. Med. crít. (Col. Mex. Med. Crít.) [online]. 2017, vol.31, n.2, pp.74-77. ISSN 2448-8909.

It has been considered that beta-blockers are used to reduce adrenergic overstimulation in septic patients. Therefore, we designed a case-control study to identify if chronic use of beta-blockers is related to less 30-day mortality among septic patients. We review medical records of ICU admission. In total, we included 104 patients divided into two groups: beta-blockers (n = 16) and control (n = 88). Patients in the study group showed no difference in mortality relative to control (p = 0.99), however the cardiovascular SOFA was higher (p = 0.05), required higher dose of vasopressors (p = 0.18) and longer stay in UTI (p = 0.11). The chronic use of beta-blockers was not protective factor for mortality in septic patients.

Keywords : Beta blockers; sepsis; septic shock; vasopressors; mortality.

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