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Cirugía y cirujanos
On-line version ISSN 2444-054XPrint version ISSN 0009-7411
Abstract
DEMIR, Demirhan O. et al. Effect of Re-TUR time on recurrence and progression in high-risk non-muscle-invasive bladder cancer. Cir. cir. [online]. 2022, vol.90, suppl.2, pp.6-12. Epub Dec 20, 2023. ISSN 2444-054X. https://doi.org/10.24875/ciru.21000905.
Objective:
We aimed to investigate the significance of time to re-staging transurethral resection (re-TUR) on recurrence and progression rates in patients with high-risk non-muscle-invasive bladder cancer as a prospective randomized study.
Methods:
The patients were randomly separated into three groups according to Re-TUR timing. In Groups 1, 2, and 3, the time interval between initial and re-TUR was 14-28 days, 29-42 days, and 43-56 days, respectively. Cox regression analysis was used to assess the effect of time from initial TUR to re-TUR on oncological outcomes.
Results:
Twenty patients in Group 1 (14-28 days), 22 patients in Group 2 (29-42 days), and 29 patients in Group 3 (43-56 days) completed the study. Kaplan–Meier plots showed no differences in recurrence-free survival (RFS) and progression-free survival (PFS) rates between the three groups. Cox regression analysis demonstrated that only tumor number was found to be a prognostic factor on RFS rates.
Conclusion:
Our prospective study demonstrated that time laps from initial TUR to re-TUR did not significantly affect on RFS and PFS rates.
Keywords : Non-muscle invasive bladder cancer; Restaging transurethral resection; High grade; Oncological outcomes.
