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Cirugía y cirujanos
versão On-line ISSN 2444-054Xversão impressa ISSN 0009-7411
Resumo
GODINEZ-VIDAL, Ansony R.; CARRILLO-ESPER, Raúl e CABELLO-AGUILERA, Ricardo. Biomarkers and sepsis endotypes. New evidence. Cir. cir. [online]. 2021, vol.89, n.4, pp.553-558. Epub 03-Nov-2021. ISSN 2444-054X. https://doi.org/10.24875/ciru.20001734.
Background:
Sepsis is an important cause of disease and death worldwide, and it has a complex and heterogeneous disease process. It is now recognized that biological markers improve sepsis classification and may facilitate the identification of different subclasses or endotypes of patients.
Objective:
To analyze the current concepts in translational biology that help to understand the heterogeneity in the response of the patient with sepsis.
Conclusions:
There are a number of biomarkers that could be useful for constructing endo-compound types that predict uncomplicated results in sepsis. These endotypes could help identify patients who deserve early antimicrobial onset or discontinuation.
Palavras-chave : Sepsis; Biology; Endotypes; Biomarkers.