Resumo

ARECHIGA-FLORES, Carlos Fernando et al. Hypocalcemia in the dairy cow. Review. Rev. mex. de cienc. pecuarias [online]. 2022, vol.13, n.4, pp.1025-1054.  Epub 11-Nov-2022. ISSN 2448-6698.  https://doi.org/10.22319/rmcp.v13i4.5277.

Calcium (Ca) levels decrease in blood and cytosol at the time of calving, altering nerve impulse transmission, muscle contraction, and immune cell activity. In the nervous system, Ca participates in the conduction of stimuli. In the muscular system, it decreases contractions, causing alterations in smooth muscle, uterus and mammary gland. In the uterus, there is retention and storage of uterine fluids and waste, with bacterial complications. In the immune system, the function of neutrophils is important, and it manifests itself with a decrease in cells engaged in phagocytosis, predisposing to mastitis and metritis. In bovine hypocalcemia, two manifestations are distinguished: clinical and subclinical. In the clinical one (Ca values less than 5.5 mg/dl), homeostasis alters, with loss of appetite, decubitus and lethargy. Subclinical hypocalcemia is more common (Ca between 8.0 and 5.5 mg/dl), and homeostasis does not alter, but muscle contraction and immune function decrease. The treatment is based on the application of calcium orally in standing cows, and intravenously in prostrate cows. Prevention depends on the inclusion of rations that contain anionic salts, which favors the stimulus to maintain blood Ca levels to control the level of cations and anions. In addition, Ca can be administered orally. Calcium homeostasis in lactation is regulated by the serotonin hormone, which stimulates the parathyroid hormone and bone resorption in osteoclasts.

Palavras-chave : Hypocalcemia; Dairy cow; Homeostasis; Calcium; Serotonin; Metritis.

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