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Nova scientia

On-line version ISSN 2007-0705


MANRIQUEZ AVILA, Aidee; ROCHA NAVARRO, Miriam Lucía; RIVAS BEJAR, Carlos Daniel  and  PEREYRA NOVARA, Texar Alfonso. Haemodynamic effects of using articaine with epinephrine in hypertensive and no hypertensive patients under oral surgery. Nova scientia [online]. 2015, vol.7, n.14, pp.254-267. ISSN 2007-0705.


The local anaesthesia is one of the procedures most used in practice surgical. In the tooth extraction, it is used to produce analgesic and anaesthetic effects. However, there is controversy about safety on having applied a local anaesthetic combined with a vasoconstrictor (epinephrine) in controlled hypertensive patients. The objective is to determine changes in mean arterial blood pressure, heart rate and blood oxygenation in normotensive and controlled hypertensive patients after the administration of truncal anaesthesia using articaine with epinephrine to 1:200 000 to perform jaw oral surgery.


Randomized controlled clinical trial in 30 subjects who attended the University of La Salle Bajio AC for jaw oral surgery. Two groups were formed of 15 subjects each according to the criteria of ASA. Both groups were registered the mean arterial blood pressure, heart rate and blood oxygenation at baseline, at 5 and 10 minutes after applying anaesthetic, and at the end of the surgical procedure. To assess the effectiveness analgesic was shown an analogic visual scale. To evaluate the changes were used the t test and two-way ANOVA.


The sample consisted of 14 women and 16 men with aged between 18-89 years old, with a mean ± standard deviation of 48.53 ± 19.37 years. When dividing by groups, the hypertensive patients showed a significant difference in age (t= -2.75; p=0.01). There were no statistically significant differences between the groups for heart rate, mean arterial pressure and blood oxygenation in any of the surgical times after administration of the local anaesthetic. In the analogic visual scale, no difference were observed between the groups (p=0.246 ).


There were no haemodynamic changes induced by the injection truncal local of articaine with epinephrine to 1:200 000 in patients with controlled hypertension during surgical procedures. However, we consider it essential that the Dentist performs the necessary precautions in the controlled hypertensive patient and promotes strategies that decrease the cardiovascular complications.

Keywords : Local anaesthesia; hypertensive patients; haemodynamic changes; vasoconstrictor.

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