Abstract

SANTANA-CRUZ, Alejandra; FLORES-MORENO, Jorge Luis; GUERRA-GONZALEZ, Roberto  and  MARTINEZ-ORTIZ, María de Jesús. Antibacterial Activity of Pipemidic Acid ions-MgFeAl Layered Double Hydroxide Hybrid Against E. coli and S. typhi. J. Mex. Chem. Soc [online]. 2016, vol.60, n.2, pp.62-66. ISSN 1870-249X.

An anion exchange process was used to prepare pipemidic acid-MgFeAl composite from MgFeAl-Cl layered double hydroxide as inorganic matrix. The obtained hybrid material contains pipemidic acid anions as well as, in a less extent; carbonate and chloride species in its interlayer space. The antibacterial properties were evaluated against E. coli and S. typhi strains through dilution broth method. MgFeAl-Cl matrix resulted to be completely inactive against two bacteria, while MgFeAl-PIP composite killed all colonies of E. coli after 90 min of exposure and showed a good activity to kill S. typhi bacteria at times as short as 120 min.

Keywords : layered double hydroxide; pipemidic acid; hybrid material; intercalation; antibacterial activity.

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