Convenient Reductive Amination of Aldehydes by NaBH4/Cation Exchange Resin

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Journal of the Mexican Chemical Society

Print version ISSN 1870-249X

Abstract

SETAMDIDEH, Davood and SEPEHRADDIN, Farhad. Convenient Reductive Amination of Aldehydes by NaBH₄/Cation Exchange Resin. J. Mex. Chem. Soc [online]. 2014, vol.58, n.1, pp.22-26. ISSN 1870-249X.

Different secondary amines have been synthesized by reductive amination a variety of aldehydes and anilines with NaBH₄/DOWEX(R)50WX8 as reducing system in THF at room temperature in high to excellent yields of products (85-93%).

Keywords : NaBH₄; DOWEX(R)50WX8; Reductive amination; Carbonyl compounds.

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