Resumen

CARDENAS-GALINDO, Luis Edilberto et al. Efficient Synthesis of 1,5-disubstituted-1H-tetrazoles by an Ugi-azide Process. J. Mex. Chem. Soc [online]. 2013, vol.57, n.4, pp.283-289. ISSN 1870-249X.

Abstract A series of eighteen novel 1,5-disubstituted-1H-tetrazoles has been prepared with moderate to good overall yields using an Ugi-azide reaction as key step under mild conditions. Tetrazoles are heterocyclic systems present in several synthetic products which have privileged biological activity. Therefore, in this paper we describe the synthesis of novel compounds containing the tetrazole moiety, which could present biological activity.

Palabras llave : Multicomponent reactions; Ugi-azide; 1,5 dipolar electrocyclization; tetrazole; azide; isocyanide.

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