Abstract

MANZANERA-ESTRADA, Mayra et al. Electrochemical Study of the Complex [Cu(pdto)(H₂O)]²⁺ (pdto =1,8-bis(2-pyridyl)-3,6-dithiaoctane) in the Presence of the Superoxide. Toward an Electrochemical Method to Measure SOD Activity. J. Mex. Chem. Soc [online]. 2013, vol.57, n.3, pp.192-197. ISSN 1870-249X.

This work presents the electrochemical characterization of Cu(NO₃)₂•2.5H₂O, [Cu(pdto)H₂O](PF₆)₂ and superoxide ion in DMSO. The electrochemical processes Cu(II) + 2e → Cu(0), [Cu(pdto)(H₂O)]²⁺ + 1e → [Cu(pdto)]⁺, [Cu(pdto)]⁺ + 1e → Cu(0), O₂ ↔ O₂ + 1e^-, and O₂^•- + 1e + H⁺ → OOH^-were identified. The electrochemical response of a mixture of the complex [Cu(pdto)(H₂O)]²⁺ with superoxide was studied and, according to this result, it was possible to establish a simple methodology that indicates if a compound presents a superoxide dismutase (SOD)-like mechanism.

Keywords : Copper (II) complex; pdto=1,8-bis-(2-pyridyl)-3,6-dithiaoctane; SOD mechanism; electrochemistry.

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