Abstract

MOHTAT, Bita; FARSIJANI, Saeedeh; RAZAGHI, Maryam  and  DJAHANIANI, Hoorieh. Reaction Between 7-Hydroxy Coumarin, Alkyl Isocyanides and Dialkyl Acetylenedicarboxylate: Synthesis of 4H-Chromenes and 1-Azabuta-1,3-dienes. J. Mex. Chem. Soc [online]. 2013, vol.57, n.2, pp.92-95. ISSN 1870-249X.

The reactive intermediate generated by the addition of tert-butyl and 1,1,3,3-tetramethyl butyl isocyanide to dialkyl acetylenedicarboxylate was trapped by 7-hydroxycoumarin to produce highly functionalized 4H-chromenes in fairly good yields. When the reaction is performed with cyclohexyl isocyanide, 1-azabuta-1,3-dienes were obtained.

Keywords : 7-hydroxycoumarin; dialkyl acetylenedicarboxylates; alkyl isocyanides; multicomponent reactions.

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