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Journal of the Mexican Chemical Society

versión impresa ISSN 1870-249X

Resumen

AVELAR, Mayra  y  MARTINEZ, Ana. Do Casiopeinas® Prevent Cancer Disease by Acting as Antiradicals? A Chemical Reactivity Study Applying Density Functional Theory. J. Mex. Chem. Soc [online]. 2012, vol.56, n.3, pp.250-256. ISSN 1870-249X.

The main goal of this investigation is to study the possible mechanisms of Casiopeinas® as anticancer agents. Electrodonating (χ-) and electroaccepting (χ+) electronegativity were calculated applying Density Functional Theory. Two different anticancer mechanisms of Casiopeínas® are proposed. There might be antiradical molecules preventing the formation of cancer cells or these molecules could reduce the amount of GSH and as a result over-produce free radicals, increasing the oxidative stress which in turn kills the cancer cells.

Palabras clave : Copper Compounds; Casiopeinas®; Electrodonating; Electroaccepting; Electronegativity; Anticancer; Free Radicals.

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