Resumen

ABASS, Mohamed; MOHAMED, Elhossain A.; ISMAIL, Mostafa M.  y  MAYAS, Aisha S.. Preparation and Some Reactions with 3-(Quinolin-3-yl)-3-Oxopropanoic Acid. J. Mex. Chem. Soc [online]. 2011, vol.55, n.4, pp.224-232. ISSN 1870-249X.

Preparation of quinolinyl-3-oxopropanoic acid 2 was accomplished by hydrolysis of pyranoquinolinedione 1 in aqueous alkaline medium. The chemical behavior of this β-keto acid 2 towards nitrosation, coupling with a diazonium salt, esterification, condensation with 2,2-dimethoxyethanamine, hydrazinolysis, Knoevenagel condensation with isatine, salisyaldehyde, 3-formylquinolones, and 3-formylchromone, was investigated. Also many of the products of these reactions were found obtainable using either pyranoquinolinedione 1 or β-keto acid 2, under the same conditions.

Palabras llave : Quinolin-2(1H)-one; β-Keto-carboxylic acid; Pyrano[3,2-c] quinoline; Knoevenagel condensation; heterocyclization reactions.

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