Resumo

CAMACHO-LUIS, Abelardo et al. Antioxidant Constituents of Geranium bellum Rose. J. Mex. Chem. Soc [online]. 2008, vol.52, n.2, pp.103-107. ISSN 1870-249X.

Radical scavenging assay-guided fractionation of the antioxidant EtOAc and MeOH extracts from the aerial parts of Geranium bellum resulted in the isolation of β-sitosterol 3-O-β-D-glucopiranoside (1), quercetin 3-O-α-L-(2"-O-acetyl)arabinofuranoside (2), quercetin 3-O-α-L-arabinofuranoside (3), quercetin (4), methyl gallate (5), gallic acid (6), methyl brevifolin carboxylate (7), and dehydrochebulic acid trimethyl ester (8). These substances were fully characterized by 1D and 2D NMR spectroscopy as well as by their physical properties. 2,2'-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging activities for the extracts, primary fractions and pure compounds were determined. Compounds 2-4 showed very strong ABTS radical scavenging activity, whereas compound 5-8 had moderate activity and compound 1 was weakly active. Compounds 2, 7 and 8 are isolated for the first time from Geranium.

Palavras-chave : Geranium bellum Rose; Geraniaceae; antioxidant activity; flavonoids; tannins; ¹H and ¹³C NMR spectroscopy.

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