Resumen

QUISPE-SICCHA, R. M. et al. Implementation of Polyvynil-Alcohol Mixed With Nano-Particles as a Near Representation of Biological Tissue: Ultrasonic and PhotoThermal Study. J. appl. res. technol [online]. 2012, vol.10, n.1, pp.63-72. ISSN 2448-6736.

We present experimental results related to the manufacturing of phantoms based on polyvinyl-alcohol (PVA) mixed with SiO₂, graphite and Ag nanoparticles. These phantoms are dummy representations of the human tissue of the breast gland. We focus our attention on the representation of the optical and the mechanical properties of the actual biological healthy tissue and of that representing a hidden cancer tumor (lesion). The quality of the samples is tested by ultrasonic imaging and laser induced photothermal (PT) detection technique. From the former test, the mechanical contrast that one can achieve is apparent. Instead, the laser detection technique makes it possible to determine that the optical contrast is achievable. For the laser induced PT method we register the so-called photothermal amplitudes, rather known as photoacoustic (PA) signals. These are the ultimate expression of laser-induced bursts of photothermal processes, whose engine is the fraction of the optically absorbed energy that decays through non-radiative channels. In our case we look for the conditions at which the PT phenomena are produced by a hidden dummy-tumor alone; meaning that the output signals are nearly free from substantial contributions from the bulk of the phantom. This is so as to mimic the actual mechanical and optical absorption performance of breast tissue with an inner cancer tumor. From the ultrasound images one can see how apparent the resemblance with the actual human tissue is.

Palabras llave : Polyvinyl-alcohol; nanoparticles; photothermal; ultrasound; phantom.

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