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Revista mexicana de neurociencia

versión On-line ISSN 2604-6180versión impresa ISSN 1665-5044

Resumen

RUIZ-SANDOVAL, José L. et al. Wallenberg syndrome and isolated lateral bulbar infarction: Clinical characteristics and prognosis in a cohort of Mexican patients. Rev. mex. neurocienc. [online]. 2021, vol.22, n.1, pp.3-9.  Epub 23-Abr-2021. ISSN 2604-6180.  https://doi.org/10.24875/rmn.20000021.

Background:

Wallenberg syndrome (WS) is a classic neurologic disorder secondary to vascular pathology of the vertebrobasilar circulation.

Methods:

Consecutive patients > 18 years with WS and isolated lateral medullary infarction syndrome were included from two Mexican hospitals. Risk factors, initial signs, symptoms, radiological findings, and acute treatment were evaluated; the prognosis was assessed using the Glasgow Outcome Scale.

Results:

Twenty-six patients were studied in a 26-year period (1988-2014); 17 patients were men (67%); and the average age was 45 years (range 19-77). Fourteen patients were under 45 years old (54%). The most common risk factors were dyslipidemia (41%) and hypertension (37%). The main initial symptoms were vertigo-dizziness (89%) gait ataxia (70%), and crossed-sensory deficit; and the main signs were crossed-sensitive deficit (93%), Horner syndrome (85%), and nystagmus (82%). In the bivariate analysis, age under 45 years was associated with a vertebral arterial dissection (p = 0.001), and age > 45 with atherothrombotic etiology (p = 0.01). About 96% of patients presented good recovery at an average of 17 months follow-up.

Conclusion:

Non-atherosclerotic vasculopathy was the main cause of WS-ILBI in young people. The clinical characteristics were similar to those reported in other series with a usually benign prognosis.

Palabras llave : Postero-lateral bulbar infarct; Stroke; Vertebral artery dissection; Wallenberg’s syndrome.

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