SciELO - Scientific Electronic Library Online

vol.16 número1Association Between Hepatitis B Virus and Chronic Kidney Disease: a Systematic Review and Meta-analysisHigh Clinical Manifestation Rate in an Imported Outbreak of Hepatitis E Genotype 1 Infection in a German Group of Travellers Returning from India índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados




Links relacionados

  • No hay artículos similaresSimilares en SciELO


Annals of Hepatology

versión impresa ISSN 1665-2681


ALTAMIRANO-BARRERA, Alejandra; BARRANCO-FRAGOSO, Beatriz  y  MENDEZ-SANCHEZ, Nahum. Management Strategies for Liver Fibrosis. Ann. Hepatol. [online]. 2017, vol.16, n.1, pp.48-56. ISSN 1665-2681.

Liver fibrosis resulting from chronic liver injury are major causes of morbidity and mortality worldwide. Among causes of hepatic fibrosis, viral infection is most common (hepatitis B and C). In addition, obesity rates worldwide have accelerated the risk of liver injury due to nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). Also liver fibrosis is associated with the consumption of alcohol, or autoimmune hepatitis and chronic cholangiophaties. The response of hepatocytes to inflammation plays a decisive role in the physiopathology of hepatic fibrosis, which involves the recruitment of both pro- and anti-inflammatory cells such as monocytes and macrophages. As well as the production of other cytokines and chemokines, which increase the stimulus of hepatic stellate cells by activating proinflammatory cells. The aim of this review is to identify the therapeutic options available for the treatment of the liver fibrosis, enabling the prevention of progression when is detected in time.

Palabras llave : Liver fibrosis; Cirrhosis; NASH; Viral hepatitis; Autoimmune liver diseases.

        · texto en Inglés     · Inglés ( pdf )