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Boletín médico del Hospital Infantil de México
versão impressa ISSN 1665-1146
Resumo
MARQUEZ-GONZALEZ, Horacio; IBARRA RIOS, Daniel; JEAN TRON, María G. e BARAJAS-NAVA, Leticia A.. Use of sildenafil for pulmonary hypertension in neonates. Bol. Med. Hosp. Infant. Mex. [online]. 2020, vol.77, n.4, pp.202-206. Epub 29-Set-2020. ISSN 1665-1146. https://doi.org/10.24875/bmhim.20000041.
Pulmonary arterial hypertension is a multifactorial nosological entity that increases neonatal mortality as a result of heart failure. Pulmonary vasodilators are the cornerstone of treatment, of which sildenafil is the most commonly used drug. Therefore, the results of a recently updated Cochrane systematic review are summarized, in which the efficacy and safety of sildenafil for the treatment of pulmonary hypertension in neonates was evaluated.
Palavras-chave : Newborn; Pulmonary arterial hypertension; Sildenafil; Mortality; Systematic review.