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Boletín médico del Hospital Infantil de México

versión impresa ISSN 1665-1146

Resumen

FLORES-MONTES, Olivia A.; VALLE-LEAL, Jaime; ARREGUIN-REYES, Roberto  y  ARMENTA-VELDERRAIN, Jesús M.. Risk factors related to cardiovascular complications in patients diagnosed with Kawasaki disease in northwestern Mexico. Bol. Med. Hosp. Infant. Mex. [online]. 2018, vol.75, n.3, pp.145-152. ISSN 1665-1146.  http://dx.doi.org/10.24875/bmhim.m18000019.

Background:

Kawasaki disease (KD) is an acute systemic vasculitis of small and medium vessels, which occurs primarily in children; it manifests itself as a febrile syndrome coupled with vasculitis data and can cause coronary artery abnormalities in 25% of untreated patients. The objective of this study was to describe the clinical behavior and to identify risk factors for cardiovascular complications in pediatric patients with KD, in a second level hospital in Northwestern Mexico.

Methods:

Under a case series design, we studied pediatric patients with diagnosis of KD. We measured clinical variables, laboratory values and the presence of cardiac complications; the probability of risk was determined with odds ratio (OR) and the association with chi squared test.

Results:

12 patients were included, and the female gender predominated; the mean age of presentation of KD was 2 years. The clinical presentation was complete in 100 % of the cases and patients also presented atypical manifestations. 50% of the patients studied had cardiovascular complications, the most common of which was coronary disease (33%). The variables male gender, age under 2 years and anemia reported OR of 5.5 and 10 to present cardiovascular complications.

Conclusions:

Cardiovascular complications of KD are frequent (more than 30%). Male gender, age under 2 years and anemia increase the probability of risk for the presence of cardiovascular complications.

Palabras llave : Kawasaki disease; Clinical behavior; Aneurysms; Myocarditis; Immunoglobulin.

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