SciELO - Scientific Electronic Library Online

vol.68 número2Leprosy: a modern assessment of an ancient neglected diseaseOncocercosis: ¿la próxima enfermedad eliminable en México? índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados




Links relacionados

  • No hay artículos similaresSimilares en SciELO


Boletín médico del Hospital Infantil de México

versión impresa ISSN 1665-1146


QUANDELACY, Talia; HOLTZ, Meredith  y  FRANCO-PAREDES, Carlos. Are leprosy reactions autoinflammatory diseases?. Bol. Med. Hosp. Infant. Mex. [online]. 2011, vol.68, n.2, pp.127-129. ISSN 1665-1146.

There are two types of leprosy reactions: reversal reactions or type 1 and erythema nodosum leprosum or type 2. Deformity and disability associated with leprosy are frequently the result of uncontrolled or untreated reactions. Although there is current availability of glucocorticoids as the mainstay of therapy, much needs to be learned about the etiology, risk factors, and pathogenesis of leprosy reactions. There is some evidence that leprosy reactions may represent, particularly, erythema nodosum leprosum autoinflammatory disease due to the aberrant activation of the innate immune system. The role for herpesviruses influencing autophagy in macrophages needs to be evaluated in the pathogenesis of leprosy reactions.

Palabras llave : autoinflammatory; erythema nodosum leprosum; reactions; leprosy.

        · texto en Inglés     · Inglés ( pdf )


Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons