Boletín médico del Hospital Infantil de México
versión impresa ISSN 1665-1146
JASSO-GUTIERREZ, Luis; MORALES-RIOS, Olga y MEJIA-ARANGURE, Juan M.. Tendency of the consumption and weighted average price over the cost of anti-infective drugs in a pediatric hospital. Bol. Med. Hosp. Infant. Mex. [online]. 2010, vol.67, n.4, pp.344-351. ISSN 1665-1146.
Background. We undertook this study to evaluate the tendency of the consumption (defined as daily doses/100 bed-days), the weighted average price (WAP) and the total cost of antibacterials, antimycotics, antimycobacterials and antiviral subgroups from 2005 to 2007, as well as the influence of the consumption and the WAP on the total costs. Methods. We used the database of the hospital pharmacy in order to calculate consumption, WAP and total cost of each drug for therapeutic subgroups. Multiple linear regression and Spearman correlation coefficient were used for statistical analyses. Results. The antibacterial subgroup showed the highest consumption and the total cost. The antiviral subgroup showed the highest WAP. Consumption and WAP had a significant influence on the total costs. The change by each unit of consumption and WAP produced an increase of 190,893.8 USD (95% CI 118,196.1-263,591.6) and 3,050.4 USD (95% CI 1,912.5-4,188.3), respectively. Conclusion. The progressive percentage increase of the total cost of anti-infective drugs in comparison with the total cost of hospital's therapeutic subgroups was due to the consumption and WAP. Statistical analysis and percentage of variations can identify the effect of consumption and WAP on total costs according to therapeutic subgroups. The analysis of high-cost drugs allows interpretation of some behaviors. Therefore, it is recommended to carry out these types of evaluations so as to identify the different variables that can influence costs.
Palabras llave : anti-infective drugs; systemic use; cost; defined daily doses; weighted average price; pediatric hospital.