Boletín médico del Hospital Infantil de México
versão impressa ISSN 1665-1146
CALZADA-LEON, Raúl; DORANTES-ALVAREZ, Luis Miguel e BARRIENTOS-PEREZ, Margarita. Mexican society for pediatric endocrinology's recommendations for the use of human biosynthetic growth hormone in children and adolescents. Bol. Med. Hosp. Infant. Mex. [online]. 2005, vol.62, n.5, pp. 362-374. ISSN 1665-1146.
The aim of this paper is to present consensus guidelines for the diagnosis and treatment of children and adolescents with growth hormone deficiency, and to alert on several crucial points regarding the use of human biosynthetic growth hormone: a) the mechanism of action of natural human growth hormone; b) how to establish clinical suspicious of growth hormone deficiency; c) utility of different biochemical studies to confirm growth hormone deficiency; d) physical and chemical characteristics of the commercial kits of growth hormone; e) how to prepare and use the growth hormone kits to ensure their efficacy; f) general objectives of growth hormone treatment; g) formal indications for the use of human growth hormone; h) define dose, time and periodicity during treatment; i) efficacy parameters of growth hormone treatment; j) factors that modify the efficacy of growth hormone treatment; k) safety parameters during growth hormone treatment; l) when, how and in who stop the treatment with growth hormone.
Palavras-chave : Growth hormone; pituitary; somatotropin; short stature.