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Boletín médico del Hospital Infantil de México

versión impresa ISSN 1665-1146


QUERO-HERNANDEZ, Armando; SANCHEZ-NAVARRO, Luis M.; SOCORRO-LOPEZ, Zoila  y  CARRASCO-DAZA, Daniel. Angiocentric cutaneous lymphoma in a 14 year old female adolescent. Bol. Med. Hosp. Infant. Mex. [online]. 2005, vol.62, n.1, pp. 50-56. ISSN 1665-1146.

Introduction. The cutaneous lymphoma is a malignant lymphoproliferative process of B or T, cells with a variety of clinical manifestation without extracutaneous disease at the time of diagnosis. There are case reports in the literature which have associated prior cutaneous injuries, with cutaneous lymphoma as determined by photosensitization. The present case report is of a female patient with diagnosis of cutaneous angiocentric lymphoma which resembled hydroa vacciniform. Case report. Female adolescent 14 year of age who was admitted to Hospital General Dr. Aurelio Valdivieso in the State of Oaxaca, Mexico. Eight months prior to hospital admission she presented dermatosis in areas exposed to the sun, characterized by vesicles, papules which evolved to ulcers and necrosis in arms and legs, she also presented with hepatosplenomegaly and facial edema. The histopatology of the lesions revealed angiodestructive, angiocentric vasculitis with atypical lymphocytes and paniculitis. The diagnosis of angiocentric cutaneous lymphoma was made. The patient was treated with combined chemotherapy with involution of her dermatosis and systemic findings. Conclusion. The present case fulfills the histopathology and clinical criteria of an angiocentric cutaneous lymphoma, with suitable response to combined chemotherapy based on anthracyclines.

Palabras llave : Hydroa vacciniforme; angiocentric vasculitis; angiocentric cutaneous lymphoma.

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