Resumo

GONZALEZ-MELCHOR, Laila; VILLARREAL-MOLINA, Teresa; ITURRALDE-TORRES, Pedro  e  MEDEIROS-DOMINGO, Argelia. Sudden cardiac death in individuals with normal hearts: an update. Arch. Cardiol. Méx. [online]. 2014, vol.84, n.4, pp.293-304. ISSN 1665-1731.  https://doi.org/10.1016/j.acmx.2014.04.002.

Sudden death (SD) is a tragic event and a world-wide health problem. Every year, near 4-5 million people experience SD. SD is defined as the death occurred in 1 h after the onset of symptoms in a person without previous signs of fatality. It can be named «recovered SD» when the case received medical attention, cardiac reanimation effective defibrillation or both, surviving the fatal arrhythmia. Cardiac channelopathies are a group of diseases characterized by abnormal ion channel function due to genetic mutations in ion channel genes, providing increased susceptibility to develop cardiac arrhythmias and SD. Usually the death occurs before 40 years of age and in the autopsy the heart is normal. In this review we discuss the main cardiac channelopathies involved in sudden cardiac death along with current management of cases and family members that have experienced such tragic event.

Palavras-chave : Sudden death; Cardiac channelopathies; Long QT syndrome; Brugada syndrome; Catecholaminergic polymorphic ventricular tachycardia; Mexico.

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