SciELO - Scientific Electronic Library Online

vol.76 suppl.2Vulnerable plaque actual and future identification methods author indexsubject indexsearch form
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • Have no similar articlesSimilars in SciELO


Archivos de cardiología de México

On-line version ISSN 1665-1731Print version ISSN 1405-9940


GONZALEZ PACHECO, Héctor. From thrombin hypothesis to inflammation: It is reality?. Arch. Cardiol. Méx. [online]. 2006, vol.76, suppl.2, pp.233-238. ISSN 1665-1731.

The classical pathophysiologic concept of the acute coronary syndromes is the coronary artery thrombosis as a consequence of rupture or vulnerable atherosclerotic plaques. Actually, it is also been considered that systemic inflammatory phenomenon play a central role in the plaque instability associated to the atherothrombotic activity of the tissue factor (TF). The throm-botic phenomenon is controlled by tissue factor, stimulating the way of the protease's active receptors (PAR) and cause a negative cycle between inflammation and coagulation.

Keywords : Acute coronary syndrome; Inflammation; Thrombin.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License