Resumo

SERMENT-GUERRERO, Jorge; BRENA-VALLE, Matilde  e  ESPINOSA-AGUIRRE, Javier. The SOS response of Escherichia coli. TIP [online]. 2005, vol.8, n.2, pp.99-105. ISSN 1405-888X.

Living organisms are continously exposed to genetic damage caused by a wide diversity of agents, either external, such as radiations and different types of biomolecules, or internal, such as free radicals and reactive oxigen species generated during oxidative metabolism. DNA damage may in turn lead to mutations and cellular or oganismic death. Therefore, to cope with such effects and in order to minimize risks, different strategies have evolved in time. Among those strategies, there is the bacterial SOS response, a group genes related to repair and damage tolerance mechanisms and whose expression rises upon DNA damage. As a result, chances of cell recovery and bacterial survival to stress have considerably increased.

Palavras-chave : lexA; recA; DNA repair; SOS response.

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