Abstract

RENTERIA-ARELLANO, María del Carmen; TORRES-CISNEROS, Juan Roberto  and  BALLESTEROS LOYO, Hugo de Jesús. Perioperative management of the suspected patient or confirmation of COVID-19 infection. Cir. gen [online]. 2020, vol.42, n.2, pp.138-148.  Epub Oct 04, 2021. ISSN 1405-0099.  https://doi.org/10.35366/95374.

SARS-CoV-2 affects the host using the angiotensin-converting enzyme 2 receptor (ACE2). The first step in virus entry is the binding of the virus trimeric protein S (spike) to the human ACE2 receptor. which is expressed in multiple organs, including the lung, heart, kidney and intestine, and more importantly in endothelial tissue. Within the main pathophysiology is the cytokine storm, it is the uncontrolled systemic inflammatory response that results from the release of large amounts of pro-inflammatory cytokines and chemokines by immuno-effector cells. The cytokine storm binds to the metabolic response to surgery trauma, causing an inflammatory hyper response, which can lead to multiple organ failure. The management of the patient with COVID-19 disease and surgery involves different medical and surgical specialties.

Keywords : COVID-19; perioperative management; personal protective equipment; cytokines.

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