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Cirujano general

versión impresa ISSN 1405-0099


CHAPA-LOBO, Alberto Félix et al. Hereditary colorectal cancer: synchronous presentation of colorectal cancer and cholangiocarcinoma in a patient with familial adenomatous polyposis. Cir. gen [online]. 2020, vol.42, n.1, pp.50-56.  Epub 24-Sep-2021. ISSN 1405-0099.

The gastrointestinal polyposis syndromes are characterized by the presence of multiple polyps in the digestive tract, affecting the colon and rectum in the most cases. Recognized family syndromes represent around 5% of colorectal cancers, the most common being familial adenomatose polyposis (FAP) and hereditary nonpolyposis colon cancer (Lynch syndrome). They are a group of diseases of low incidence with very varied characteristics, which require a correct individualization for their most appropriate treatment. Within the genetic syndromes, there are presentations with typical molecular variations that typecast the most frequent groups, however there is the possibility that these syndromes present genetic similarities whose predominance will determine the evolution and presentation of the disease.

Palabras llave : Adenomatose polyposis; Lynch syndrome; hereditary colorectal cancer.

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