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Cirujano general

versão impressa ISSN 1405-0099


MORENO-PAQUENTIN, Eduardo et al. Case report of a giant gastrointestinal stromal tumor and review of the literature. Cir. gen [online]. 2018, vol.40, n.2, pp.127-132. ISSN 1405-0099.


Gastrointestinal stromal tumors (GIST) represent a group of non-epithelial rare tumors with an estimated incidence of 10 to 20 per million persons. GISTs can present at any age but more commonly in persons between ages of 40 and 70 years. They arise more frequently from the stomach and have Kit gene mutation.

Material and methods:

We presented a case of a 39-year old male with a giant abdominal tumor with surgical resection and review of the literature of GIST.


A wedge resection of a GIST measuring 49 × 45 × 15 cm was performed. Microscopically, it was a spindle-shaped tumor cells GIST, low-grade histology (1), pT4 (more than 10 cm), with an intermediate risk (mitotic count less than 5 per 50 HPF and more than 10 cm) and complete resection (R0).


In this case, we describe the clinical presentation and the diagnosis algorithm of a low grade giant gastric GIST. To our knowledge, this could represent the biggest GIST reported in the literature.

Palavras-chave : Gastrointestinal stromal tumor; GIST; surgical oncology; SCARE.

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