Resumen

GUZMAN, Angel; DIAZ, Eduardo; TREJO, Blanca E.  y  LOPEZ-MUNOZ, Francisco J.. Synthesis of Potential Anti-inflammatory Compounds, Selective Inhibitors of Cyclooxygenase-2 (COX-2). Rev. Soc. Quím. Méx [online]. 2004, vol.48, n.4, pp.230-234. ISSN 0583-7693.

Seven compounds were synthesized as potential anti-inflammatory drugs, selective inhibitors of the enzyme cyclooxygenase-2 (COX-2). The structural design was based on the knowledge of the active site of the enzyme. The synthesized compounds present a combined naproxen and celecoxib structures.

Palabras llave : Cyclooxygenase; anti-inflammatory drugs; naproxen; celecoxib; synthesis.

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