Revista latinoamericana de química
versão impressa ISSN 0370-5943
ORTIZ NUNEZ, Yarelis; SPENGLER SALABARRIA, Iraida; COLLADO, Isidro G. e HERNANDEZ-GALAN, Rosario. Antifungal activity of extracts and terpene constituents of aerial parts of Juniperus Lucayana. Rev. latinoam. quím [online]. 2010, vol.38, n.3, pp. 145-152. ISSN 0370-5943.
Ethanolic and hexane extracts from the aerial parts of Juniperus lucayana were assayed against the phytopathogenic fungus Botrytis cinérea by the poisoned food technique. The hexane extract showed to have a higher antifungal activity than ethanolic extract. Fractionation of hexane extract by silica gel open column chromatography and HPLC afforded seven known compounds sandaracopimaric acid (1), 4-epi-dehydroabietic acid (2), oplopanone (3), oplodiol (4), nephtediol (5), 7α-hydroxycallitrisic acid (6), and 7-oxocallitrisic acid (7). Compound 1 showed a significative fungal growth inhibition during the assay. The effect of compounds 2-7 on spore germination fungus was also studied.
Palavras-chave : Juniperus lucayana; terpenoids; antifungal activity; Botrytis cinerea; growth inhibition; spore germination.