Abstract

GARCIA COLMENERO, Irma; DIAZ FRANCO, Sandra Danahé; ZORRILLA MENDOZA, Jazibeth Guadalupe  and  CORTES CHAMORRO, Rebeca. Security issues in pain management with nonsteroidal anti-inflammatory drugs. Rev. sanid. mil. [online]. 2018, vol.72, n.5-6, pp.324-331.  Epub Aug 23, 2019. ISSN 0301-696X.

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most consumed drugs worldwide, with or without medical prescription, mostly for the symptomatic treatment of a widely range of diseases characterized by acute or chronic pain. NSAIDs have a heterogenous chemical structure that gives them antipyretic, anti-inflammatory and analgesic properties through their ability to inhibit proinflammatory prostaglandins. The variability in risk profiles among NSAIDs forces the medical community to individualize their use based on the personal characteristics of the patients as well as the expertise of the physician. NSAIDs should be used for short cycles of treatment with the lowest doses possible, using them in a range of clinical efficacy, with specific monitoring of gastrointestinal, cardiovascular, renal hepatic and hematologic complications. The objective of this work is to review the safety aspects of the treatment with NSAIDs in chronic analgesic management.

Keywords : NSAIDS; acute pain; chronic pain; anti-inflammatory agents.

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