OBJECTIVE:

To know the reproductive results in an embryo transfer program on day 4 and compare them with transfers in D3 and D5

MATERIALS AND METHODS:

A prospective analysis comprised a period from March 2015 to July 2017, with 306 couples undergoing an IVF / ICSI procedure and who met the inclusion criteria (patients of all ages, cycles captured and transferred in fresh and patients with all the factors of infertility) and exclusion (cases of ovodonation, cycles in which there were no embryos to be transferred and cycles in which embryo transfer was difficult). The population was divided into 3 groups: Group A with transferred on day 3; Group B with transferred on day 4) and Group C with transferred on day 5 (TE D5). The luteal phase support for the 3 groups was with progesterone vaginally for 14 days. Pregnancy rates per transfer day were evaluated with the number of clinical pregnancies regarding the number of transfers made and comparing the results with a chi-square test considering significant differences with p < 0.05.

RESULTS:

We analyze 306 couples. Group A with 205 patients transferred on day 3 (TE D3); Group B with 62 patients transferred on day 4 (TE D4) and Group C with 39 patients transferred on day 5 (TE D5). A significant difference (p = 0.035) was found between the pregnancy rate on day 3 and 4 for patients over 40 years of age (11.4% and 31.6% respectively), however, an increase tendency was observed at all ages. in the pregnancy rate when the embryo transfer takes place on day 4.

CONCLUSIONS:

The embryo transfer on day 4 of development can be considered as one more option, to present better results with respect to the transfers made on day 3, and a very viable alternative in transfers made in D5 with very similar pregnancy rate and in this even greater study.

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