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Ginecología y obstetricia de México

versión impresa ISSN 0300-9041


GOMEZ DE SEGURA BLANCO, R et al. Early embryo bisection: Nine cases description. Ginecol. obstet. Méx. [online]. 2017, vol.85, n.11, pp.763-771. ISSN 0300-9041.


The cases in which the embryo divides in two identic embryos is causing real concerns in the treatments of assisted reproduction. The percentage of early bisection in natural conception is about 0.4% on life birth. There is noticed an increase of this cases in treatments of the assisted reproduction, especially when transferring in blastocyst stage.


We have collected series of 9 cases in a retrospective way, between 2014-2016 in which we have transferred 1 embryo and we have visualized 2 sacs, and the cases in which we have transferred 2 embryos and we have visualized 3 sacs. This year we have transferred a total of 3737 embryos, 1470 fresh embryo transfers and 827 frozen embryo transfers. These 9 cases mean the 0.39% of early embryo division and the 0.86% of total of pregnancies.


We didn’t observe a relationship in the risk of embryo division with the hatching. Neither with advanced age of the eggs, non the father’s age. The rate of division of the embryos in cycles of the assisted reproduction in our clinic using ICSI increase in comparison with the spontaneous gestations, howbeit it would be necessary to do more studies in order to prove this statement. We consider single embryo transfer the best practice in IVF in young women or donor eggs.

Palabras llave : Early bisection; Blastocyst; Embryo transfer.

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