Abstract

CARRILLO ESPER, Raúl et al. Ferritin and hiperferritinemic syndrome: Its impact on the seriously ill; current concepts. Rev. Asoc. Mex. Med. Crít. Ter. Intensiva [online]. 2015, vol.29, n.3, pp.157-166. ISSN 0187-8433.

Ferritin is an iron-binding molecule that stores iron for vital cellular processes, but also plays a role in a large number of other conditions, including inflammatory, neurodegenerative and malignant diseases. A markedly elevated serum ferritin has been associated with inflammatory conditions such as adult-onset Still's disease, macrophage activation syndrome, Sepsis and Septic shock and catasthrophic antiphospholipid syndrome. Hyperferritinemia is associated with increased mortality, multiple organ dysfunction syndrome and critical illness so the hyperferritinemic syndrome must be kown by the intensivist. The aim of this paper is to present current concepts related to ferritin and hyperferritinemic syndrome.

Keywords : Ferritin; hyperritinemic syndrome; sepsis.

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