Resumen

RIVAS-SANTIAGO, Bruno Tonatiuh; TORRES ROJAS, Martha; BOBADILLA LOZOYA, Karen  y  SADA DIAZ, Eduardo. Immunological role of epithelial cells of the lung. Rev. Inst. Nal. Enf. Resp. Mex. [online]. 2005, vol.18, n.4, pp.321-326. ISSN 0187-7585.

The respiratory tract is one of the main systems which is in perennial contact with a wide variety of pathogenic microorganisms; however, infection is seldom produced due to its innate immune response. Respiratory tract epithelial cells play a very important role to avoid colonization of the lung by infectious agents, because they recognize microbial molecules through very specialized receptors, such as toll-like receptors; moreover, these cells posses a broad variety of molecules which are related to local immunity. Respiratory tract epithelial cells produce chemokines, antimicrobial peptides and other proinflammatory molecules that prevent the establishment of pathogenic microorganisms

Palabras llave : Epithelial cells; antimicrobial peptides; defensins; innate immunity.

        · resumen en Español     · texto en Español     · Español ( pdf )