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Perinatología y reproducción humana
versión On-line ISSN 2524-1710versión impresa ISSN 0187-5337
Resumen
CARRERA-MUINOS, Sandra et al. Evolution of newborns with persistent pulmonary hypertension in a neonatal intensive care unit. Perinatol. Reprod. Hum. [online]. 2022, vol.36, n.2, pp.40-45. Epub 01-Dic-2022. ISSN 2524-1710. https://doi.org/10.24875/per.22000005.
Background:
Persistent pulmonary hypertension (PPHN) occurs in 2 to 6 out of 1,000 live newborns, with mortality between 4 and 33%.
Objective:
To learn the frequency, evolution and morbidity of the disease.
Material and method:
Of 71 patients the sample was divided into two groups, Group A: 44 (61.97%) surviving patients and Group B: 27 (38%) deceased. Standard percentages, averages and deviations were calculated, in addition to Students T, Square Chi and OR IC95%.
Results:
There was a significant difference in the weight of the groups, where surviving patients had greater birth weight. In 54.93% hypertension was primary and 45.07% secondary. Endotracheal intubation increased 1.2 times the risk of mortality, the use of polytherapy does not decrease the risk of mortality. Within complications 88.1% pulmonary dysplasia development, there was no difference in the presence of dysplasia.
Conclusion:
PPHN was associated with high morbidity in newborns, survivors were more weight, intubation increased the risk of mortality, there were no differences in pharmacological therapy. 88% developed bronchopulmonary dysplasia. Mortality occurred at 38%.
Palabras llave : Persistent pulmonary hypertension; Mechanical ventilation; Respiratory failure.
