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Perinatología y reproducción humana

On-line version ISSN 2524-1710Print version ISSN 0187-5337

Abstract

CARRERA-MUINOS, Sandra et al. Evolution of newborns with persistent pulmonary hypertension in a neonatal intensive care unit. Perinatol. Reprod. Hum. [online]. 2022, vol.36, n.2, pp.40-45.  Epub Dec 01, 2022. ISSN 2524-1710.  https://doi.org/10.24875/per.22000005.

Background:

Persistent pulmonary hypertension (PPHN) occurs in 2 to 6 out of 1,000 live newborns, with mortality between 4 and 33%.

Objective:

To learn the frequency, evolution and morbidity of the disease.

Material and method:

Of 71 patients the sample was divided into two groups, Group A: 44 (61.97%) surviving patients and Group B: 27 (38%) deceased. Standard percentages, averages and deviations were calculated, in addition to Student’s T, Square Chi and OR IC95%.

Results:

There was a significant difference in the weight of the groups, where surviving patients had greater birth weight. In 54.93% hypertension was primary and 45.07% secondary. Endotracheal intubation increased 1.2 times the risk of mortality, the use of polytherapy does not decrease the risk of mortality. Within complications 88.1% pulmonary dysplasia development, there was no difference in the presence of dysplasia.

Conclusion:

PPHN was associated with high morbidity in newborns, survivors were more weight, intubation increased the risk of mortality, there were no differences in pharmacological therapy. 88% developed bronchopulmonary dysplasia. Mortality occurred at 38%.

Keywords : Persistent pulmonary hypertension; Mechanical ventilation; Respiratory failure.

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