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Perinatología y reproducción humana
versión On-line ISSN 2524-1710versión impresa ISSN 0187-5337
Resumen
CORIA-LORENZO, José de J. et al. Gram-negative susceptibility patterns in a tertiary pediatric hospital: 2013 vs. 2018. Perinatol. Reprod. Hum. [online]. 2021, vol.35, n.3, pp.89-98. Epub 30-Sep-2022. ISSN 2524-1710. https://doi.org/10.24875/per.21000006.
Background:
Gram-negatives continue to be the cause of infections associated with health care (HCAI).
Material and methods:
We analyzed the antimicrobial resistance of pathogens during 2013 vs. 2018 and we compare it with what was published in 2006 vs. 2012.
Results:
We identified 9 gram-negative pathogens, out of a total of 404 isolates, with a prevalence in 2013 (N = 227 [0.22]) vs. 2018 (N = 177 [0.17]) and an incidence due to discharges (6,607 in 2013 and 7,778 in 2018) of 3.4 and 2.2%, respectively.Three pathogens stood out Klebsiella pneumoniae (129 [31.93%]), Pseudomonas aeruginosa (85 [21.03%]) and Escherichia coli (80 [19.80%]). These, called ESKAPE-E pathogens, prevailed as the cause of HCAI. We identified an increase in resistance patterns for many pathogens in 2018.
Conclusion:
Multi-resistance to ESKAPE-E pathogens is a serious public health problem, due to the lack of therapeutic alternatives to face this challenge. Bacterial resistance maps help in antibiotic prescription.
Palabras llave : Antimicrobial susceptibility; Bacterial resistance; Gram-negatives; Microbiological map.
