Background:

Mechanical ventilation continues to be an essential tool in the care of premature newborns, there is evidence that volume-limited ventilation (VLV) has advantages over pressure-limited ventilation (VLP).

Objective:

To determine the clinical and gasometric evolution in newborns I preterm VLV compared to VLP.

Material and methods:

It was an observational and analytical research in a neonatal intensive care unit, where 80 newborns were included ≤ 32 weeks of gestation and ≤ 1000 grams at birth divided into two groups.

Results:

Statistically significant difference was observed in ventilation days, favouring VLV (p=0.002); in hypoxemia and hypocarbia variables, which are directly affected by ventilatory mode, lower degree of affection was found in VLV but without statistical difference. It was found in the group of patients with VLV lower respiratory acidosis (p=0.05), and lower FIO2 requirements (p=0.04).

Conclusion:

Like literature, our results prove benefits such as decreased ventilation days, decreased acidosis and lower needs of FIO2 with the use of VLV.

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