Abstract

TENA SUCK, Martha Lilia; FABIAN SAN MIGUEL, María Guadalupe; MOLINA CARDENAS, Hugo Roberto  and  PARRAGUIRRE MARTINEZ, Sara. Cerebral changes in hipertensive disease duping pregnancy. Arch. Neurocien. (Mex., D.F.) [online]. 2004, vol.9, n.4, pp.215-221. ISSN 1028-5938.

The maternal mortality rate in eclapsia varies from 0 to 20 percent in contemporany medical literature, The death of a patient may be viewed as the result a variable association of factors within a limited cl0inicophatologic and therapeutic spectrum . The largest percentage of preclampsia and eclampsia is attributed to cerebrovascular complications, primary cerebral hemorrhage and renal and hepatic failure. Disseminated intravascular coagulation is a contributed condition in 15% of hypertension death. Objective: the present is a descriptive study that was based on the analysis of clinical, laboratory and morphologic data, attempts to identify the major factor that influences the course of eclampsia, principally the neurological and cerebral findings. Results: we studied of a total 30 cases of necropsy due to eclampsia. 11 were preclampsia, and 19 cases were eclampsia, 15 cases with HELP syndrome. AII cases presented increase of arterial pressure, more than 100 mmHg of systolic pressure. 60 % presented gestasional disease of the 3 ^rd trimester. And de 40% in the second trimestry. The cerebral hemorrhage were the most important cerebral macroscopical findings, presented in the 33%, in the temporal lobe, 23% in cerebellum and occipital lobe in the 26%, pontine hemorrhage in 33%, and petechial hemorrhage in the white matter in the 33% and brain edema and hipoxic encephalopaty in all cases.

Keywords : preclampsia; eclampsia; cerebral hemorrhage; cerebral finding necropsia.