Resumen

NUNEZ-BARREIRO, Luis Roberto; ECHAVE-AVALOS, Jorge Alberto  y  GUTIERREZ-COTA, Fernando. Stauffer’s syndrome as manifestation of clear cell renal carcinoma. Med. interna Méx. [online]. 2019, vol.35, n.5, pp.807-812.  Epub 30-Abr-2021. ISSN 0186-4866.  https://doi.org/10.24245/mim.v35i5.2628.

The incidence of clear cell renal carcinoma corresponds to about 2% of all malignant neoplasms. The classic triad of hematuria, abdominal pain and palpable mass is estimated in 10% of cases. Stauffer described in 1961 the first case called nonmetastatic hepatophrenic dysfunction syndrome, this condition can be found in 3 to 20% of cases. The involvement of liver enzymes may be related to metastatic liver infiltration or also due to non-metastatic dysfunction. It is a rare manifestation in renal cancer. Before the finding of elevated liver enzymes and alkaline phosphatase, ruling out both anatomic and functional hepatic impairment, Stauffer syndrome should be suspected, being able to make the difference between going unnoticed or being a timely finding. This paper reports a little frequent manifestation of paraneoplastic syndrome of clear cell renal carcinoma.

Palabras llave : Stauffer syndrome; Clear cell renal carcinoma; Paraneoplastic syndrome.

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