SciELO - Scientific Electronic Library Online

 
vol.34 issue2Value of C-reactive protein (CRP)/albumin index in the diagnosis of sepsis.Differences in electrocardiographic changes in HIV patients with and without treatment with protease inhibitors vs NNRTI. author indexsubject indexsearch form
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • Have no similar articlesSimilars in SciELO

Share


Medicina interna de México

Print version ISSN 0186-4866

Abstract

FELIX-BULMAN, Jorge Andrés et al. Adjustment of the glycated hemoglobin value to diagnose diabetes mellitus in Mexico. Med. interna Méx. [online]. 2018, vol.34, n.2, pp.196-203. ISSN 0186-4866.  http://dx.doi.org/10.24245/mim.v34i2.1902.

BACKGROUND

Nowadays, the American Diabetes Association (ADA) recognizes the use of three tests for the diagnosis of diabetes mellitus, including the determination of glycated hemoglobin (HbA1c).

OBJECTIVE

To evaluate if the established value of 6.5% of glycated hemoglobin for the diagnosis of diabetes mellitus is applicable to the Mexican population.

MATERIAL AND METHOD

A descriptive, transversal and analytic study was done in October 2016 in persons that were subjected to a capillary test for HbA1c and serum glucose.

RESULTS

There were included 388 subjects in whom it was determined that the age and the sex did not influence on the obtaining of a determinate level of HbA1c. Capillary HbA1c test tended to diagnose a greater number of cases of prediabetes (170 vs 63) and diabetes (27 vs 13) compared with serum glucose test, with a difference in the number of healthy persons between the two groups of 121 (191 healthy persons with HbA1C and 312 healthy persons with serum glucose); however, both variables shared a 90.2% of similarity (p < 0.001). It was obtained a new threshold of HbA1C for the diagnosis of diabetes of 6.65% (with sensitivity and specificity of 76% and 97%, respectively).

CONCLUSION

With the new cutoff value the incidence of cases of diabetes decreased in the HbA1c group, with a reduction of 7% to 4.9% (27 to 19 cases).

Keywords : Diabetes; Glycated hemoglobin.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )