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Medicina interna de México

Print version ISSN 0186-4866


ARELLANO-NAVARRO, Consuelo Estephani et al. Value of C-reactive protein (CRP)/albumin index in the diagnosis of sepsis. Med. interna Méx. [online]. 2018, vol.34, n.2, pp.188-195. ISSN 0186-4866.


Sepsis is one of the main causes of morbidity and mortality worldwide, in this entity the impact of the inflammatory response can worsen the patient’s prognosis.


To find out if there is a correlation between the C-reactive protein (CRP)/albumin index and SOFA and qSOFA scores that allow us to establish its utility as a diagnostic tool.


A cross-sectional analytical study carried out from July 2016 to June 2017 at the Emergency Department of the General Hospital Xoco, SEDESA. We included patients who were diagnosed with sepsis using SOFA and qSOFA scales in whom the CRP/albumin index was determined. We then proceeded to search for correlation between these measurements.


There were included 30 patients. There was no correlation between qSOFA (p = 0.79) and SOFA (p = 0.40) scores with the CRP/albumin index. This index was lower in females (p = 0.03). We found a statistically significant relationship of hospital death with a lower CRP/albumin index (p = 0.05). Other variables that correlated with death were age (p = 0.01) and SOFA (p = 0.02).


There is no significant correlation between CRP/albumin index and qSOFA and SOFA score in the diagnosis of sepsis. A lower CRP/albumin index was found in female patients and who died in hospital. Other variables that correlated with death were age and SOFA score.

Keywords : Sepsis; C-reactive protein; SOFA.

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