Abstract

ROMERO-GONZALEZ, JP; CARRILLO-ESPER, R; MEZA-MARQUEZ, JM  and  SOSA-GARCIA, JO. Up-to-date in the management of fever in patients with sepsis and septic shock: controversies and recommendations based on evidence. Med. interna Méx. [online]. 2017, vol.33, n.1, pp.99-108. ISSN 0186-4866.

Fever is the result of a systemic inflammatory response that can be triggered by numerous stimuli, which can be a double-edged sword, because it can have beneficial effects, such as improved immune response and suppress bacterial growth, but also harmful effects, such as up to six times higher metabolic rate, causing hyperdynamia that in cardiac patients is poorly tolerated and even increases lung damage mediated by cytokines. Therefore several questions arise about how and when to control fever in septic patient; however, current evidence is limited, but it can be concluded that the thermal control must be performed with temperatures above 38.5oC with physical means and if not, give antipyretics is suggested.

Keywords : fever; sepsis; paracetamol; thermal control.

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